DSRI may refer to:
Danish Space Research Institute Deep-Sea Research Part I: Oceanographic Research Papers, a scientific journal published by Elsevier Defence and Security Research Institute, an institute of the Royal Military College of Canada Democratic and Secular Republicans of Iran, a political alliance; see Political parties in Iran Dopamine-serotonin reuptake inhibitor, also known as Serotonin-dopamine reuptake inhibitor Democratic and Secular Republicans of Iran