Prentis is a surname. Notable people with the surname include:

Brooke Prentis (born 1980), Australian Aboriginal Christian leader Dave Prentis (born 1950), British trade unionist, General Secretary 2001–2021 Edmund Prentis (1883–1967), American engineer and art collector Edward Prentis (1797–1854), English genre painter Henning Webb Prentis Jr. (1884–1959), American industrialist John Prentis (c. 1726–c. 1775), mayor of Williamsburg, Virginia from 1759 to 1760 Joseph Prentis (1754–1809, American politician, Speaker of the Virginia House of Delegates 1786–88 Richard Prentis (born 1947), South African rugby union player Robert R. Prentis (1855–1931), American lawyer, 16th Chief Justice of Virginia 1926–31 Victoria Prentis (born 1971), British Conservative Party politician, Member of Parliament (MP) for Banbury since 2015 William Prentis (1699–1765), Virginia merchant

Fictional characters Ava Prentis, a character in Nexo Knights Prentis (Ninjago), a character in Ninjago

See also Prentis Cobb Hale (1910–1996), American entrepreneur Prentis Hancock (1942–2025), British actor

See also Prentiss