Keserű and Keserü or Keșerü (Romanian spelling), English transliteration: Kesheru, are Hungarian-language surnames. They may refer to:
Alajos Keserű, Hungarian water polo player Ferenc Keserű, Hungarian water polo player Ferenc Keserű (cyclist), Hungarian cyclist Etelka Keserű, Hungarian economist and politician
Ilona Keserü, Hungarian artist Katalin Keserü, Hungarian artist and professor emeritus in arts
Claudiu Keșerü, Romanian footballer