The rates of adverse effects of aripiprazole are:

Adults

Very common (>10% incidence)

Weight gain Headache Agitation Insomnia Anxiety Nausea & vomiting Akathisia — a sense of unease and restlessness that presents itself with anxiety Lightheadedness Constipation Emotional instability Euphoria or Dysphoria

Common (1–10% incidence)

Dizziness Dyspepsia — indigestion Somnolence — which is usually mild and transient and less severe than that seen with most antipsychotics. Fatigue Restlessness Dry mouth Extrapyramidal side effects (e.g. dystonia, parkinsonism, tremor, myoclonic jerks, etc.) Orthostatic hypotension Musculoskeletal stiffness Abdominal discomfort Blurred vision Cough Pain Myalgia Rash Rhinitis

Uncommon (0.1–1% incidence)

Leukopenia Thrombocytopenia Bradycardia (low heart rate) Palpitations Orthostatic hypotension Dry eye Photophobia Diplopia Eyelid oedema Photopsia Diarrhoea Gastritis Pathological gambling Dysphagia Gastroesophageal reflux disease Swollen tongue Oesophagitis Hypoaesthesia oral Face oedema Gait disturbance Chills Discomfort Feeling abnormal Mobility decreased Self-mutilation Heart rate increased Blood glucose increased Pyrexia Blood prolactin increased Blood urea increased Electrocardiogram QT prolonged Blood bilirubin increased Hepatic enzyme increased Increased appetite Nocturia Polyuria Pollakiuria Incontinence Urinary retention Sexual dysfunction Amenorrhoea Pruritus Photosensitivity reaction Urticaria

Rare (<0.1%)

Neuroleptic malignant syndrome (Combination of fever, muscle stiffness, faster breathing, sweating, reduced consciousness, and sudden change in blood pressure and heart rate) Neutropenia Suicidal ideation and behavior Depression Painful and/or sustained erection (Priapism) Seizures Rhabdomyolysis Agranulocytosis Cardiopulmonary failure Myocardial infarction (heart attack) Atrial flutter Supraventricular tachycardia Ventricular tachycardia Atrioventricular block Extrasystoles Sinus tachycardia Atrial fibrillation Angina pectoris Myocardial ischaemia Pancreatitis Diabetic ketoacidosis Prolonged QT interval (less common than with most other atypical antipsychotic drugs) Speech disorder Electrolyte abnormalities including hyponatraemia, hypokalaemia, hypocalcaemia, etc. Hypertension Dysphagia Oropharyngeal spasm Laryngospasm Hepatitis Jaundice Hypersalivation Chest pain Urinary retention or incontinence Alopecia (hair loss) Photosensitivity reaction Rash Xerostomia (when given by injection) Tardive dyskinesia (As with all antipsychotic medication, patients using aripiprazole may develop the permanent neurological disorder tardive dyskinesia.) Stroke Transient Ischaemic Attack Increased body temperature Angioedema Cardiorespiratory arrest Cardiorespiratory failure

Sudden unexplained death has been reported. However, the frequency is unknown.http://www.medicines.org.uk/EMC/pdfviewer.aspx?isAttachment=true&documentid=16161

Common in children

Feeling sleepy Headache Vomiting Fatigue Increased appetite Insomnia Nausea Stuffy nose Weight gain Uncontrolled movement such as restlessness, tremor muscle stiffness

References