Domitius may refer to:
Dometius of Persia, Christian saint, d. 300s Dometius of Byzantium, Christian bishop, d. 200s Dometius, founding monk of the Monastery of the Holy Trinity, Meteora, in 1438 Saint Domitius, a French saint Domitius Afer Domitius Alexander Domitius Domitianus Gnaeus Domitius Corbulo Domitius Modestus Gnaeus Domitius Ahenobarbus (father of Nero) Domitius Marsus, poet Domitius, a minor Roman god and one of the indigitamenta Domitius (spider), a genus of scaffold web spiders Domitia gens, an ancient Roman family