Darbishire is a surname. Notable people with the surname include:
Arthur Dukinfield Darbishire (1879–1915), British zoologist Charles Darbishire (1875–1925), British politician and East India merchant Godfrey Darbishire (1853–1889), English rugby player Helen Darbishire (1881–1961), English literary scholar Henry Astley Darbishire (1825–1899), British architect Robert Dukinfield Darbishire (1826–1908), English lawyer and philanthropist
Fictional characters Charles Edwin Jeremy Darbishire, the school friend of John Jennings in the Jennings novels by Anthony Buckeridge
Other Darbishire Quad, a building and quad of Somerville College, Oxford
See also Darbyshire Derbyshire, English county