ESM may refer to:
Business and economics Election stock market Electronic Settlement Matching Elektrani na Severna Makedonija (), a power company in North Macedonia Enterprise Securities Market, a market of the Irish Stock Exchange Enterprise service management European Single Market European Stability Mechanism
Education Eastman School of Music, in Rochester, New York, United States Eastport-South Manor Central School District, in New York, United States East Syracuse-Minoa Central School District, in New York, United States East Syracuse-Minoa High School, in Manlius, New York, United States École secondaire de Mirabel, a secondary school in Quebec, Canada École spéciale militaire de Saint-Cyr, a French military academy Emmanuel School of Mission Engineering science and mechanics European School, Munich, in Germany
Science and technology Earth System Model ECMAScript Modules Electronic support measures Embedded System Module End System Multicast, a research project at Carnegie Mellon University Energy Saving Module Ethosuximide, an antiepileptic drug European Service Module, part of the Orion spacecraft Event sampling methodology Experience sampling method
Transport Colonel Carlos Concha Torres Airport, serving Esmereldas, Ecuador Elsenham railway station, in England Essex station (Montana), a train station in the United States
Other uses Emergency Services Medal (Australia) Esuma language Eurasian Youth Union, a Russian political organisation European Social Movement, a defunct neo-fascist organisation European Sports Media European Supermarket Magazine Extreme Speed Motorsports, an American auto racing team