Burwell may refer to:

People Burwell (name)

Places Burwell, Cambridgeshire Burwell, Lincolnshire Burwell, Nebraska Burwell Creek, a stream in Georgia The Burwell, an NRHP-listed high-rise in Knoxville, Tennessee

Ships USS Laub (DD-263), a destroyer renamed HMS Burwell when she was transferred to the Royal Navy in World War II

Government Sylvia Mathews Burwell (born 1965), United States Secretary of Health and Human Services, who due to that role, has been named as the defendant in several related lawsuits: Burwell v. Hobby Lobby King v. Burwell Zubik v. Burwell