Fluffy may refer to:

Characters Fluffy (Harry Potter), a monstrous three-headed dog in Harry Potter and the Philosopher's Stone Fluffy, a beast in a crate that features in a segment of the 1982 film, Creepshow Fluffy, a fictional cat character in the Disney comics series Darkwing Duck Fluffy, a one-shot character in the episode, "Puppy Love" on the Pajanimals Fluffy, a fictional pet elephant belonging to the character Oscar the Grouch on the TV series Sesame Street Fluffy, a fictional pet pig belonging to the character Eric Cartman on the TV series South Park

Films Fluffy (1965 film), a 1965 film starring Tony Randall and Shirley Jones Fluffy, a 2003 short film starring Fred Ewanuick Fluffy (2016 film), a 2016 short film

Music Fluffy (band), a 1990s UK punk band Fluffy, a 1990s band associated with the band Breakfast with Amy "Fluffy" (song), a 2013 song by Wolf Alice

Other uses Fluffy, nickname for stand-up comedian Gabriel Iglesias Fluffy (comics), a 2003 graphic novel by Simone Lia Fluffy (footwear), a form of fashion accessory Fluffy transcription factor, a gene of the mold Neurospora crassa

See also Fluff (disambiguation) F.L.U.F.F.I., a fictional robot ape belonging to the Bennett family on the TV series Bionic Six Fluffing (disambiguation)