Happe or Happé is a German surname. Notable people with the surname include:
Alain Happe, French football director Dan Happe (born 1998), English footballer Francesca Happé (born 1967), British neuroscientist Heinrich Happe (1894–1979), German politician Hendrik Happé (1884–1962), Dutch architect Markus Happe (born 1972), German footballer Thomas Happe (born 1958), West German handball player Ursula Happe (1926–2021), German swimmer