Handley is a surname. Notable people with the surname include:
Brian Handley, soccer player Benjamin Handley (1784–1858), English politician and member of parliament for Boston Carol Handley, Classics educator Chris S. Handley, comic collector in United States v. Handley David Handley (farmer), activist Dick Handley (1922–2012), American football player Elizabeth Handley-Seymour (c. 1873–1948), English fashion designer Eric Handley CBE (1926–2013), professor of Greek at Cambridge and University College, London George Handley (disambiguation), multiple people, including George Handley (politician) (1752–1793), American politician from Georgia George Handley (footballer, born 1868) (1868–1938), English footballer George Handley (footballer, born 1886) (1886–1952), English footballer George Handley (footballer, born 1912) (1912–1943), English footballer George B. Handley, professor of humanities at Brigham Young University Harold W. Handley, American politician from Indiana Jody Handley, English footballer Joe Handley, Canadian politician from the Northwest Territories Lee Handley (1913–1970), Major League baseball player Mary Ann Handley (1936–2023), American politician from Connecticut Matthew Handley, radio host on Ave Maria Radio Paul M. Handley, American journalist, wrote The King Never Smiles (biography of Thai King Bhumibol) Ray Handley, American football coach Taylor Handley, actor Tommy Handley, comedian Vernon Handley, conductor Wayne Handley, airshow performer Wal Handley, motorcycle racer