N-acetylphosphatidylethanolamine-hydrolysing phospholipase D (EC 3.1.4.54, NAPE-PLD, anandamide-generating phospholipase D, N-acyl phosphatidylethanolamine phospholipase D, NAPE-hydrolyzing phospholipase D) is an enzyme with systematic name N-acetylphosphatidylethanolamine phosphatidohydrolase. It catalyses the following chemical reaction

N-acylphosphatidylethanolamine + H2O N-acylethanolamine + a 1,2-diacylglycerol 3-phosphate

This enzyme is involved in the biosynthesis of anandamide.

See also

Endocannabinoid System N-acyl phosphatidylethanolamine

References

External links

N-acyl phosphatidylethanolamine phospholipase D (NAPEPLD ((C7orf18, FMP30, NAPE-PLD)) Human Protein Atlas