Roquebrune may refer to the following communes in France:

Roquebrune, Gers, in the Gers département Roquebrune, Gironde, in the Gironde département Roquebrune, the former name for Roquebrune-Cap Martin, in the Alpes-Maritimes département Roquebrune-sur-Argens, in the Var département

Other uses 13701 Roquebrune, an asteroid