Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase () is an enzyme with systematic name ATP:methylphosphonate 5-triphosphoribosyltransferase. It catalyses the following chemical reaction:
ATP + methylphosphonate alpha-D-ribose 1-methylphosphonate 5-triphosphate + adenine
This enzyme characterised from the bacterium Escherichia coli produces α-D-ribose 1-methylphosphonate 5-triphosphate by reacting methylphosphonic acid with adenosine triphosphate (ATP), which gives adenine as a byproduct. This is part of a pathway that allows microorganisms to metabolise carbon-phosphorus bonds.
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