Cason is a surname. Notable people with the surname include:
Andre Cason, American sprinter Antoine Cason, American football player Aveion Cason, American football player Barbara Cason, American actor Buzz Cason, American rock singer Chris Cason, American voice actor Cleo S. Cason, American librarian James Cason, U.S. Foreign Service officer Jim Cason (1927–2013), American football player John L. Cason (1918–1961), American actor Lino Cason, Italian soccer player L.J. Cason (born 2006), American basketball player Rod Cason, American football player Thomas J. Cason, American politician Wendell Cason, American football player William J. Cason (1924–2017), American politician Yvette Cason, American actor