Domingo Martínez may refer to:
Domingo Martínez (baseball) (born 1965), former baseball player Domingo Martínez (footballer) (born 1982), Paraguayan footballer Domingo Martinez (author), Mexican-American author known for his memoirs (2012) Domingo Martínez de Irala (c. 1509–c. 1556), Spanish Basque conquistador Domingo Martinez (politician), American politician and New Mexico State Auditor