Brandreth is a surname. Notable people with the surname include:

Aphra Brandreth (born 1978), British politician Benjamin Brandreth (1809–1880), New York politician and patent medicine manufacturer Courtenay Brandreth (1891–1947), wildlife artist from New York George A. Brandreth (1828–1897), New York politician and patent medicine manufacturer Gyles Brandreth (born 1948), British actor, broadcaster and writer Jeremiah Brandreth (1790–1817), English activist hanged for treason Thomas Shaw Brandreth (1788–1873), inventor and classical scholar Thomas Brandreth (1825–1894), Royal Navy admiral and Lord of the Admiralty