23S rRNA (uracil1939-C5)-methyltransferase (, RumA, RNA uridine methyltransferase A, YgcA) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (uracil1939-C5)-methyltransferase. This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + uracil1939 in 23S rRNA S-adenosyl-L-homocysteine + 5-methyluracil1939 in 23S rRNA

The enzyme specifically methylates uracil1939 at C5 in 23S rRNA.

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