Charles Seymour (1885–1963) was an American academic, historian and President of Yale University.
Charles Seymour may also refer to:
Charles Seymour, 2nd Baron Seymour of Trowbridge (1621–1665) Charles Seymour, 6th Duke of Somerset (1662–1748) Charles Seymour (cricketer) (1855–1934), English cricketer Charles Gurney Seymour, a fictional character in the political novel First Among Equals, by Jeffrey Archer