Westerhoff is a surname. Notable people with the surname include:

Gay-Yee Westerhoff (born 1973), Chinese-English cellist Hans Westerhoff (born 1953), Dutch biologist and biochemist Jan Westerhoff, American philosopher and Orientalist Rembertus Westerhoff (1801-1874), Dutch politician, Thorbeckian Member of Parliament (1849-1873), general practitioner, scholar, first testator of the Groninger Museum

See also Westerhof