Van Gool is a Dutch toponymic surname, meaning "from Goirle". Gool represents an approximation of the regional pronunciation of Goirle.Gool, van at the Database of Surnames in The Netherlands. Notable people with the surname include:
Jacob van Gool (1596–1667), Dutch Orientalist and mathematician better known by his Latinized name Jacobus Golius Jan van Gool (1685–1763), Dutch painter and art historian Jean Van Gool (1931–1986), French footballer Jef Van Gool (born 1935), Belgian footballer Roger Van Gool (born 1950), Belgian footballer Wilma van Gool-van den Berg (born 1947), Dutch sprinter
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