McCaslin is a surname. Notable people with the surname include:
Bob McCaslin Jr. (born 1957), American politician Bob McCaslin Sr. (1926–2011), American politician Donny McCaslin (born 1966), American jazz saxophonist Eugene McCaslin (born 1977), American football player Jason McCaslin (born 1980), Canadian musician John McCaslin (born 1957), American talk radio host and writer Mary McCaslin (born 1946), American folk singer Matthew McCaslin (born 1957), American artist Richard McCaslin (1964–2018), American criminal Susan McCaslin (born 1947), Canadian poet
See also McCaslin Airport, an airport in Cleveland County, Oklahoma, United States McCaslin Nunatak, a nunatak of Antarctica