Matthew Thornton was a signer of the US Declaration of Independence.

Matthew Thornton or Matt Thornton may also refer to:

Matt Thornton (baseball) (born 1976), Major League Baseball relief pitcher Matt Thornton (martial artist) (born 1969), martial artist and founder of Straight Blast Gym Matthew Thornton Elementary School Matthew Thornton House SS Matthew Thornton, see List of Liberty ships Matthew Thornton, Sr., see Beale Street Matthew Thornton, mayor of Lambton, New South Wales