John Frame may refer to:
John Frame (theologian) (born 1939), American philosopher and Calvinist theologian John Frame (cricketer) (1733–1796), English cricketer John Frame (sculptor) (born 1950), American sculptor, photographer, composer and filmmaker John Frame (bishop) (1930–2017), Canadian bishop John W. Frame (1872–1932), provincial politician from Alberta, Canada John Frame (rugby union) (born 1946), Scottish rugby union player