12 gauge may refer to:

Size 12-gauge shotgun, the most popular shotgun shell 12 gauge sheet metal 12 gauge wire

Music 12 Gauge (Kalmah album), 2010 album by Finnish band Kalmah 12 Gauge (rapper) (born 1968), American rapper active in the 1990s 12 Gauge (12 Gauge album), 1994 album by the above artist Emerson Drive, a Canadian rock group known as 12 Gauge from 1995 to 2000 before moving to Nashville

Sports Paige VanZant, MMA fighter, nicknamed "12 gauge".

See also Gauge (disambiguation)