LSS may refer to:
Companies and organizations
Companies
LSS Data Systems, a medical software company Lone Star Steel Company, a tubular steel mill in Lone Star, Texas
Schools Lakeland School System, school district in Lakeland, Tennessee Laurel Springs School, Ojai, California, United States Lawrence Sheriff School, Rugby, Warwickshire Langstaff Secondary School, Richmond Hill, Ontario
Other organizations
Law Society of Saskatchewan Leicester Secular Society, the world's oldest Secular Society Life Saving Society Lithic Studies Society Lincoln Square Synagogue, Manhattan, New York City Lunds Studentsångförening, a Swedish male-voice choir
Science and technology Large-scale structure of the universe Large Space Simulator, Space simulator Life Span Study of atomic bomb survivors, see Epidemiology data for low-linear energy transfer radiation LSS (gene), an enzyme LSS (Lynxmotion Smart Servo), a series of hobbyist-grade smart actuators created by RobotShop Inc. Landing Ship Stern Chute, a converted train ferry used early in WW2 as Dock landing ship Lumbar spinal stenosis, a medical condition in which the spinal canal narrows XM26 Lightweight Shotgun System
Other uses L. S. Sheshagiri Rao, Indian writer and scholar of Kannada literature Lean Six Sigma, a synergized managerial concept of Lean manufacturing and Six Sigma Licentiate of Sacred Scripture, see Licentiate of Sacred Theology Logistics Support System Lone Star Showdown, the official rivalry between the Texas A&M Aggies and the Texas Longhorns LSS (Last Song Syndrome), a 2019 Philippine film