Michael or Mike Keane may refer to:

Michael Keane (economist) (born 1961), American-born economist Michael Keane (footballer, born 1982), former Irish footballer Michael Keane (footballer, born 1993), English footballer Michael Keane (governor) (1874–1937), British colonial administrator in India Michael Keane (hurler) (1933–2002), Irish hurler Mike Keane (born 1967), retired Canadian ice hockey player Michael Keane, a video game character in Grand Theft Auto IV Michael Keane, per historical anecdote, a blind Irish harp player at Fort Oswego

See also Michael Keen (disambiguation)