John Colthurst may refer to:
John Colthurst (1678–1756), MP for Tallow (Parliament of Ireland constituency) 1734–1756 Sir John Colthurst, 1st Baronet (died 1775), MP for Castlemartyr, Youghal and Doneraile Sir John Conway Colthurst, 2nd Baronet (c. 1743–1787), of the Colthurst baronets
See also Colthurst (disambiguation) John C. Bowen-Colthurst, Anglo-Irish soldier