Elsener is a surname. Notable people with the surname include:
Karl Elsener (inventor) (1860–1918), inventor of the Swiss Army knife Karl Elsener (footballer) (born 1934), retired Swiss football goalkeeper Patsy Elsener (born 1929), American diver who competed in the 1948 Summer Olympics Ramona Elsener (born 1992), Swiss ice dancer Rudolf Elsener (born 1953), retired Swiss football striker