Lyme or LYME may refer to:

Lyme disease, an infectious disease carried by ticks caused by bacteria of the genus Borrelia

Places

United Kingdom Lyme, an alternative name of Lyme Handley, a civil parish in Cheshire Lyme Park, an estate in Cheshire Lyme Regis, a town in Dorset commonly known as Lyme Lyme Bay, an area of the English Channel Lyme Brook, tributary stream of the River Trent, Staffordshire Forest of Lyme, a historic area of forest covering parts of Cheshire, Derbyshire, and Staffordshire Newcastle-under-Lyme, a town and borough in Staffordshire Uplyme

United States Lyme, Connecticut, a town in southeastern Connecticut, the namesake of Lyme disease Old Lyme, Connecticut, a neighboring town East Lyme, Connecticut, a neighboring town Lyme, New Hampshire, a town in western New Hampshire Lyme, New York, a town in New York along the Lake Ontario shoreline Lyme Township, Huron County, Ohio, a small town in northern Ohio New Lyme (disambiguation), several towns in the United States

Other places Lyme Park, Gauteng, a suburb of Johannesburg, South Africa

Ships English ship Lyme (1654), 52-gun third rate Speaker-class frigate built at Portsmouth, launched in 1654 HMS Lyme, any of several vessels of the British Royal Navy RFA Lyme Bay (L3007), a landing ship dock of the British Royal Fleet Auxiliary

People David Lyme (born 1966), also known as Jordi Cubino, a Catalan singer, songwriter, and model

Other uses LYME (software bundle), a solution stack consisting of Linux, Yaws, Mnesia, and Erlang Lyme Art Association, arts organization established in 1914, with roots going back to 1902 Lyme-grass or Leymus arenarius

See also Lyme and Cybelle, American folk/pop duo, 1960s Flyme (disambiguation) Glyme (disambiguation)