M44 or M-44 may refer to:
Transportation BMW M44, an inline 4 gasoline engine produced by BMW M-44 (Michigan highway), a state highway in Michigan M44 (Cape Town), a Metropolitan Route in Cape Town, South Africa M44 (Johannesburg), a Metropolitan Route in Johannesburg, South Africa M44 motorway (Hungary), an under-construction motorway MÁV Class M44, the Polish code-name for a Hungarian shunting diesel locomotive
Weaponry 44M Tas, a Hungarian medium/heavy tank design of World War II ALFA M44, a Spanish machine gun developed during World War II Hungarian 44M, an unguided anti-tank rocket designed by Hungary in World War II M44 generator cluster, an American chemical cluster bomb M44 self-propelled howitzer, 1950s US self-propelled 155 mm artillery Panssarimiina m/44, a Finnish anti-tank blast mine KP m/44, a Finnish submachine gun A model of the Mosin–Nagant, a Russian bolt-action rifle A Yugoslav People's Army's internal designation of SU-100 self-propelled gun
Other uses IBM M44/44X, an experimental IBM mainframe from the 1960s M44 (cyanide device), a device used to poison predators Messier 44 (M44), an open star cluster also called the Beehive Cluster Progress M-44, a spacecraft used to resupply the International Space Station USS Vigor (AM-473), a U.S. Navy Agile-class minesweeper The 44th Mersenne prime