Pena or Péna is a surname. Notable people with the surname include:
Afonso Pena (1847–1909), Brazilian politician Danny Pena (born 1968), American soccer player Marc Péna (born 1960), French academic and politician Marius Pena (born 1985), Romanian soccer player Paul Pena (1950–2005), American singer Trebor Pena (born 2002), American football player
See also Peña (surname)