Nafisi (Arabic: نفيسي) is an arabic surname, that translates to "precious" (Arabic: نفيسة, nafisa). It is a common arabic surname in Iran and Persian Gulf countries. Notable people with the surname include:
Abdullah Al-Nafisi (born 1945), Kuwaiti academic and politician Ahmad Nafisi (1919–2004), Iranian bureaucrat and mayor of Tehran (1961–1963) Amannisa Khan Nafisi, wife of Abdurashid Khan (1526–1560) Azar Nafisi (born 1948), Iranian-American writer and academic Habib Nafisi (1908–1984), Iranian academic Khalid Al-Nafisi (1937–2006), Kuwaiti actor Nezhat Nafisi (1920–2003), Iranian politician Saeed Nafisi (1895–1966), Iranian scholar, fiction writer and poet Mirza Ali Akbar Khan Nafisi (1847–1924) Iranian physician and scholar