Northwestern Hotel may refer to:
Northwestern Hotel (Des Moines, Iowa), listed on the National Register of Historic Places in Polk County, Iowa Northwestern Hotel (Waukesha, Wisconsin), listed on the National Register of Historic Places in Waukesha County, Wisconsin North Western Hotel, Liverpool, a grade II listed building in Liverpool, England. North Western Hotel, Morecambe, in Morecambe, England. North-Western Hotel, Livingstone, in Livingstone, Zambia