Gildersleeve is a surname. Notable people with the surname include:
Basil L. Gildersleeve (1831–1924), American classical scholar Charles Fuller Gildersleeve (1833–1906), Canadian lawyer and politician Fred Gildersleeve (1881–1958), American photographer Henry Gildersleeve (shipbuilder) (1817–1894), American shipbuilder Henry Alger Gildersleeve (1840–1923), American jurist John Gildersleeve (born 1944), British businessman Overton Smith Gildersleeve (1825–1864), Canadian lawyer and politician Sarah Gildersleeve Fife (1885–1949), American bibliophile, gardener Virginia Gildersleeve (1877–1965), American academic, long-time Dean of Barnard College Willard Gildersleeve (1886–1976), head coach of New Hampshire's football team in 1909 and Massachusetts' team in 1910 William Camp Gildersleeve (1795–1871), American abolitionist
See also Andrew Gildersleeve Octagonal Building, historic octagonal house in Mattituck, New York Gildersleeve House in Hudson, McLean County, Illinois, US Gildersleeve Mountain in Kirtland, Ohio, US The Great Gildersleeve (1941–1957), US radio comedy show, one of broadcast history's earliest spin-off programs