This article is about the particular significance of the year 1759 to Wales and its people.

Incumbents Lord Lieutenant of North Wales (Lord Lieutenant of Anglesey, Caernarvonshire, Flintshire, Merionethshire, Montgomeryshire) – George Cholmondeley, 3rd Earl of Cholmondeley Lord Lieutenant of Glamorgan – Other Windsor, 4th Earl of Plymouth Lord Lieutenant of Brecknockshire and Lord Lieutenant of Monmouthshire – Thomas Morgan Lord Lieutenant of Cardiganshire – Wilmot Vaughan, 3rd Viscount Lisburne Lord Lieutenant of Carmarthenshire – George Rice Lord Lieutenant of Denbighshire – Richard Myddelton Lord Lieutenant of Pembrokeshire – Sir William Owen, 4th Baronet Lord Lieutenant of Radnorshire – Howell Gwynne Bishop of Bangor – John Egerton Bishop of Llandaff – Richard Newcome Bishop of St Asaph – Robert Hay Drummond Bishop of St Davids – Anthony Ellys

Events 19 September – The Dowlais Iron Company is formed. date unknown – Evan Davies resigns as head of the Welsh Academy, following a rift between the Presbyterian and Congregational Fund Boards.

Arts and literature New books Blodeu-gerdd Cymry (ed. Dafydd Jones) Mathias Maurice – Social Religion Exemplify'd John Wesley – Primitive Physick, translated by John Evans of Bala

Births 1 January – Joseph Foster-Barham, owner of the Trecŵn estate (died 1832) 11 February – John Rice Jones, Welsh-born American politician (died 1824) 16 March – Sir John Nicholl, politician and judge (died 1838) 7 August – William Owen Pughe, lexicographer (died 1835) 10 September – George Herbert, 11th Earl of Pembroke (died 1827) 18 October – Theophilus Jones, historian (died 1812) date unknown - William Aubrey, engineer (died 1827) David Thomas (Dafydd Ddu Eryri), (died 1822)

Deaths 11 August – John Heylyn, Welsh-descended clergyman, 74 27 September – Isaac Maddox, Bishop of St Asaph, 62 2 November – Charles Hanbury Williams, diplomat and satirist, 50

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