The Anti-apoptotic Ras signaling cascade is an intracellular signal transduction cascade that involves the Ras protein and inhibits apoptosis. It is the target of the cancer drug gefitinib.

It may refer to the PI3K/AKT pathway.http://genesdev.cshlp.org/content/11/6/701.abstract "The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal" 1997

It may refer to the MAPK/ERK pathway which involves ras and can affect apoptosis.http://cancerres.aacrjournals.org/cgi/content/abstract/67/21/10343 "Suppression of PTEN Expression Is Essential for Antiapoptosis and Cellular Transformation by Oncogenic Ras" 2007http://www.aacrmeetingabstracts.org/cgi/content/abstract/2005/1/972-b "Pathways potentiated by oncogenic Ras to modulate apoptosis induced by anticancer agent FR901228 " 2005

The anti-apoptotic STAT pathway does not involve Ras.

See also Ras subfamily

References

External links Diagram of ras onwards.