Prynne is a surname. Notable people with the surname include:

Edward Arthur Fellowes Prynne (1854–1921), British painter George Fellowes Prynne (1853–1927), British architect George Rundle Prynne (1818–1903), British Anglo-Catholic cleric J. H. Prynne (Jeremy Halvard Prynne, 1936–2026), British poet and literary critic Michael Whitworth Prynne (1912–1977), British Army major general William Prynne (1600–1669), English Puritan politician

See also Hester Prynne, the protagonist of the novel The Scarlet Letter Prine Prinner