Kettlewell is a surname. Notable people with the surname include:
Bernard Kettlewell (1907–1979), British physician and geneticist Danielle Kettlewell (born 1992), Australian synchronised swimmer John Kettlewell (1653–1695), English clergyman Henry Kettlewell (1876–1963), British cricketer Professor Kettlewell, a villain in the Doctor Who television serial Robot Richard Wildman Kettlewell (1910-1994), official in Nyasaland Roger Kettlewell (born 1945), Canadian football player Ruth Kettlewell (1913–2007), British actress Stuart Kettlewell (b. 1984), Scottish footballer