Great Catherine may refer to:
Catherine the Great (1729–1796), leader of Russia Great Catherine: Whom Glory Still Adores, 1913 play by George Bernard Shaw Great Catherine (film), 1968 British film starring Peter O'Toole, Zero Mostel, Jeanne Moreau, and Jack Hawkins
See also Katharine the Great, Deborah Davis' 1979 biography of Katharine Graham