Clos may refer to:
People Clos (surname)
Other uses CLOS, Command line-of-sight, a method of guiding a missile to its intended target Clos network, a kind of multistage switching network Clos (vineyard), a walled vineyard; used in France, Germany and California an alternative spelling of close in the name of a Cul-de-sac Common Lisp Object System (CLOS)