Isaac Davis may refer to:

Isaac Davis (soldier) (1745–1775), Revolutionary War Minuteman captain Isaac Davis (advisor) (1758–1810), Welsh advisor to Kamehameha I Isaac Davis (lawyer) (1799–1883), lawyer active in Worcester, Massachusetts Isaac Davis (American football) (born 1972), American football player Ike Davis (born 1987), American baseball first baseman Ike Davis (shortstop) (1895–1984), American baseball shortstop Isaac Mortimer Davis, the protagonist of Woody Allen's 1979 film Manhattan

See also Isaac Davis Trail, historic trail in Massachusetts, United States Isaac Davis House, historic house in Massachusetts, United States David Isaacs (disambiguation)