Koffikro-Afféma is a village in south-eastern Ivory Coast. It is in the sub-prefecture of Maféré, Aboisso Department, Sud-Comoé Region, Comoé District. The border with Ghana is six kilometres northeast of the village.

Koffikro-Afféma was a commune until March 2012, when it became one of 1,126 communes nationwide that were abolished."Le gouvernement ivoirien supprime 1126 communes, et maintient 197 pour renforcer sa politique de décentralisation en cours", news.abidjan.net, 7 March 2012.

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