Myotomys is a genus of African Karoo rats that inhabit the Karoo, a semi-desert region in the southern portion of the African continent. Previously placed in the genus Otomys, they are sometimes referred to as vlei rats.

Species Genus Myotomys Sloggett's vlei rat (rock Karoo rat, ice rat), Myotomys sloggetti Musser, G. G. and M. D. Carleton. 2005. Superfamily Muroidea. Pp. 894-1531 in Mammal Species of the World a Taxonomic and Geographic Reference. D. E. Wilson and D. M. Reeder eds. Johns Hopkins University Press, Baltimore. Bush vlei rat, Myotomys unisulcatus

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