Terence or Terrence O'Brien may refer to:
Terence O'Brien (bishop) (1600–1651), Irish Roman Catholic bishop of Emly Terence O'Brien (British Army officer, died 1865), British Army officer and acting governor of Ceylon Sir Terence O'Brien (colonial administrator) (1830–1904), British Army officer and governor of Newfoundland, 1889–1895, son of the above Terence O'Brien (actor) (1887–1970), Irish-born British actor Terence O'Brien (rower) (1906–1982), English Olympic rower Terence O'Brien (British diplomat) (1921–2006), British ambassador to Nepal, 1970–1974, Burma, 1974–1978, and Indonesia, 1978–1981 Terence O'Brien (New Zealand diplomat) (1936–2022), New Zealand ambassador to the United Nations, 1980–1983, 1990–1993, and the European Community, 1983–1986 Terrence L. O'Brien (born 1943), United States federal judge Terrence O'Brien (director) (born 1953), American founder and director of the Hudson Valley Shakespeare Festival