A technical knockout (TKO) is a professional fighting term.

TKO may also refer to:

Sports TKO, the names of two professional wrestling moves referring to either the cutter or stunner variant TKO Group Holdings, a combat sports company

Music Artists TKO (band), a rock band from Seattle, Washington TKO, a pop group led by Katie White

Albums TKO (Tsakani Mhinga album), 2000 TKO (The Knock Out), 2018 album by Mýa TKO, album by Kelly Khumalo, 2005

Songs "TKO" (song), by Justin Timberlake, 2013 "TKO", from Bassnectar's Unlimited, 2016 "TKO", from Jesse Malin's The Fine Art of Self Destruction, 2002 "TKO", a song by Le Tigre from the 2004 album This Island "TKO", a song by Motion City Soundtrack from the 2015 album Panic Stations "TKO", from the Sam & Max Season Two Soundtrack "T.K.O.", by Giant Panda, 2005 "T.K.O.", from Womack & Womack's debut album Love Wars, 1983 "T.K.O. (Boxing Day)", from Elvis Costello's Punch the Clock, 1983 "T.K.O.", from Dave Grusin's Migration, 1989 "TKO", from Ive's Ive Empathy, 2025 "TKO (Knock You Out)" a 2003 song by Bubbles

Film and TV "TKO" (Babylon 5), a 1994 television episode T.K.O. (film), a 2007 film starring Dianna Agron The Kill Order, the prequel novel to The Maze Runner series Three Kingdoms Online, a browser based strategy game TKO: Total Knock Out, an obstacle course reality TV game show T.K.O., an OK K.O.! Let's Be Heroes character TKO, an unsold game show hosted by Peter Tomarken

Technology Taylor KO Factor, a measurement of the stopping power of a firearms cartridge TKO Software, a defunct software company Triple knockout, in molecular biology "To keep open", a medical acronym for an intravenous drip that is flowing just enough to keep the IV open for future use (sometimes written as KVO—"keep vein open")

Other uses The Kindness Offensive, a North London group known for random acts of kindness Tie knock out, a railroad maintenance vehicle also known as a tie extractor Tseung Kwan O, a new town in Hong Kong MTR station code for Tseung Kwan O station Station code for Taman Kota railway station in West Jakarta, Indonesia TKO Studios, a comics publisher

See also KO (disambiguation) Knockout (disambiguation)