De Ribera is a Spanish surname. Notable people with the surname include:
Alonso de Ribera (1560–1617), Spanish soldier Fernando Afán de Ribera, 3rd Duke of Alcalá de los Gazules, (1583–1637), Spanish noble and diplomat Juan de Ribera (1532–1611), Spanish Roman Catholic archbishop Jusepe de Ribera (1591–1652), Spanish painter Pedro de Ribera (1681–1742), Spanish Baroque architect