Interstate 335 may refer to: Interstate 335 (Iowa), a designation once proposed by city leaders in Carlisle and Des Moines, Iowa for the Des Moines Bypass Interstate 335 (Kansas), a spur to Topeka, Kansas and designation for part of the Kansas Turnpike Interstate 335 (Minnesota), a never-built spur in Minneapolis, Minnesota Interstate 335 (Oklahoma), the designation for the Kickapoo Turnpike