Mangudadatu is a surname. Notable people with the surname include:
Esmael Mangudadatu (born 1968), Filipino politician Dong Mangudadatu (born 1970), Filipino politician Mariam Mangudadatu (born 1973), Filipina politician Pax Mangudadatu, Filipino politician Pax Ali Mangudadatu (born 1997), Filipino politician Suharto Mangudadatu (born 1969), Filipino politician