PMO may refer to:
Government and military Polish Military Organisation, an intelligence and sabotage group during World War I Prime Minister's Office (disambiguation), government departments in several countries Principal Medical Officer, a senior position Priority Material Office, a logistics support command of the United States Navy Privatization and Management Office, a Philippine government agency
Science Periodic mesoporous organosilica, a form of silica Phosphorodiamidate morpholino oligo, a biochemical Planetary-mass object, in astronomy Prosopometamorphopsia, a visual disorder
Other uses Falcone Borsellino Airport, Italy (IATA code: PMO) Pine Mountain Observatory, an astronomical telescope in Oregon, US Project management office, a internal standards group pmo, 2020s slang for 'piss me off'